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This is consistent with the mechanistic hypothesis that semaglutide, through its GLP-1 receptor-mediated effects, protects pancreatic -cell function and improves glucose tolerance by regulating insulin secretion 34

In this report, we share: Expected population-level mortality and morbidity impacts for these four markets under central, optimistic and pessimistic scenarios

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doi: 10.1016/S0040-4020(01)90096-1

The trajectory suggests exciting possibilities, but also key research gaps